Epstein File EFTA01205594: Ro Khanna, Susan Wild and Khanna (DS9)

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Epstein File EFTA01205594: Ro Khanna, Susan Wild and Khanna (DS9)

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Technical genetic research excerpt discussing DNA repair mechanisms, specifically non-homologous end joining (NHEJ) and its role in creating small insertion/deletion mutations.

👤 Named in This Document

Susan Wild Wild Ro Khanna

🔑 Evidence Keywords

insertion perform targeted

📋 Key Excerpts9

PersonKeyword

Excerpt 1

Alternatively, repair by non- 256 homologous end joining (NHEJ) produces a small **insertion**/deletion mutation, protecting the site from future 257 recognition

Excerpt 2

**Khanna**, K. K. & Jackson, S. P. DNA double-strand breaks: signaling, repair and the 232 cancer connection. Nat. Genet. 27, 247-254 (2001). 233 22.

Excerpt 3

EFTA01205604 a b Endonuclease) **Wild** type Gene drive **Wild** type (A) Target gene Homologous chromosomes Gene drive (D) Recoded target Endonuclease cargo